PostDoc in Molecular and Functional Neurobiology Group (m/f): Luxembourg, Luxembourg
The University of Luxembourg is a multilingual, international research University.
The University of Luxembourg has the following vacancy in the Luxembourg Centre for Systems Biomedicine (LCSB):
PostDoc in Molecular and Functional Neurobiology Group (m/f)
Ref.: R-AGR-0242-10-C ( Model IPD)
Fixed-term contract 24 months,
Full-time position (40h/week)
Start date: as soon as possible
Employee status
Research project:
The postdoctoral fellow will be involved in the ATTRACT project entitled: “Modelling idiopathic Parkinson’s disease-associated somatic variation in dopaminergic neurons”. The aim of this FNR-funded research we aim to investigate the involvement of the mitochondrial genome in the pathogenesis of Parkinson's disease using stem cell-derived cellular models and postmortem brain tissue.
Your tasks/mission:
Generation/maintenance of induced pluripotent stem cells and subsequent differentiation into dopaminergic neurons
Design and application of experiments to assess the impact of mtDNA defects on mitochondrial and neuronal function
Application of single-cell analysis approaches to post-mortem tissue sections (histology, quantitative immunofluorescence, laser capture micro dissection)
Student supervision
For further information, please contact Prof. A. Grünewald at anne.gruenewald@uni.lu
Your profile:
PhD in Cellular Biology, Neuroscience, or related discipline
Strong interest in interdisciplinary research and cellular models of neurodegeneration
Track record in research and laboratory work as documented by publications in internationally acknowledged journals
Profound knowledge of molecular genetics, biochemistry and cell biology
Expertise with inducible pluripotent stem cell models
Experience with histology, immunofluorescence analysis and laser capture microdissection
Previous experience with CRISPR/Cas9 gene editing desirable
Excellent communication, team-working and interpersonal skills
Previous experience as supervisor of students
Enthusiasm and great commitment to research
Very good command of the English language
We offer:
Fully funded position with the possibility of renewal for up to 5 years depending on availability of funding
Exciting international research environment
Opportunity to participate in the development of the LCSB
Travel opportunities to national and international meetings as well as participation in specialized trainings
The University of Luxembourg offers competitive compensation and is an equal opportunity employer
Applications (in English) should contain the following documents:*
Detailed Curriculum Vitae including a list of publications
Cover letter mentioning the reference number
Description of past research experience and future interests
Copies of diploma and transcripts
Name and addresses of three referees
Please apply online until the 15th of October 2018
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