Post-Doctoral Research Associate: Using Synthetic Biology to engineer novel cell lines for drug discovery and testing

 

The project is to conduct key research on using synthetic biology to develop a suite of mammalian cell lines for drug discovery and testing applications. The project will focus on generating in vivo biosensors, genetic logic gate circuits for information rich cellular read outs informing on cell state and the impact of small molecule drugs and therapeutic proteins and peptides. This is an exciting and ambitious project that aims to use cutting edge Synthetic Biology (SB) approaches to develop novel systems for phenotypic (cell-based) drug screening.

 

Candidates should hold (or be about to receive) a PhD in synthetic biology, drug discovery and testing, mammalian cell biology, stem cell biology, molecular biology, molecular genetics or a related area. Research experience involving one or more of the following is desirable: synthetic biology, mammalian cell engineering, drug discovery and testing, mammalian stem cell transformation and tissue culture, epigenetics, genetic characterisation.