The JAK-STAT signaling pathway is central in cellular homeostasis and development and controls inflammation, infection and cancer. The Viennese JAK-STAT community recently attracted funding from the FWF for a Special Research Programme (SFB) on JAK-STAT signaling, chromatin remodeling and disease. It is now advertising 10 PhD positions to promising young scientists who wish to work at the cutting edge of research into the interface between inflammation, immunity and cancer.
The SFB provides a productive, tightly interconnected network for the long-term and interdisciplinary investigation of complex topics. It is hosted by the University of Veterinary Medicine Vienna ; Richard Moriggl, Mathias Müller, Veronika Sexl) and involves CeMM Austrian Academy of Sciences ; Christoph Bock), MFPL University of Vienna; Thomas Decker) and the Medical University of Vienna; Sylvia Knapp).
The SFB is studying principles that underlie switches in transcription directed by the chromatin landscape and 3D structure, such as those that occur in normal and aberrant development, in the reaction to infection and in carcinogenesis. Consortium members have expertise in areas as wide-ranging as immunity, inflammation, hematopoietic malignancies, pharmacogenomics, epigenetics, bioinformatics, ‘disease-tailored’ mouse models and genome editing. The group’s mission is to pave the way for novel therapeutic possibilities, especially with regard to personalized medicine.
PhD students will have the opportunity to perform research at the cutting edge of interdisciplinary molecular medicine and will be trained by the entire consortium and associated faculty, enabling them to help shape the future of pathway medicine. They will address key biomedical questions. The available resources and support will give them the freedom to experiment and to develop their scientific skills. An extensive programme of courses in complementary skills is offered.
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