招聘简介：
波士顿大学肺中心博斯曼实验室正在招募博士后研究员，负责感染相关免疫学和肺部炎症的研究项目。
急性呼吸窘迫综合征（ARDS）和脓毒症是微生物感染的危及生命的并发症，免疫系统受到严重干扰。在目前缺乏明确治疗方案的情况下，ARDS和脓毒症是全球卫生系统面临的一个巨大问题。我们的实验室致力于更好地了解这些炎症性疾病发病过程中的分子过程。我们实验室生产的几种新型转基因小鼠菌株将可用。
我们正在寻找积极的博士后研究员，以促进我们的实验和翻译研究。特别关注的领域是涉及炎症、病原体识别、宿主-病原体相互作用、巨噬细胞、中性粒细胞、细胞因子和相关信号通路的新基因的作用。这些项目将根据研究员的个人资格和兴趣进行量身定制。例如，可以与申请人讨论分子生物学技术、免疫学方法、生物信息学或手术小鼠模型的性质和范围。
英文原文：
The Boston University Pulmonary Center, Bosmann Lab is recruiting Postdoctoral Fellows for projects on infection-associated immunology and lung inflammation.
Acute respiratory distress syndrome (ARDS) and sepsis are life-threatening complications of microbial infections with profound disturbances of the immune system. In the current absence of definitive treatment options, ARDS and sepsis represent an enormous problem for health systems worldwide. Our laboratory is dedicated to obtain a better mechanistic understanding of the molecular processes during the pathogenesis of these inflammatory diseases. Several novel transgenic mouse strains generated by our laboratory will be available.
We are looking for highly motivated Postdoctoral Fellows to promote our experimental and translational research. Special areas of interest are the role of novel genes involved in inflammation, pathogen recognition, host-pathogen interactions, macrophages, neutrophils, cytokines and related signaling pathways. The projects will be tailored to meet the individual qualifications and interests of the Fellow. For example, the nature and extent of molecular biology techniques, immunology methods, bioinformatics or a focus on surgical mouse models can be discussed with the applicant.
The projects will involve a broad spectrum of immunology methods together with massive parallel sequencing (bulk RNA-Seq, single-cell RNA-Seq) including data analysis. Boston University houses a new Single Cell Core Facility. Another area of interest is genome editing by RNA-guided nucleases (e.g. CRISPR-Cas9) in the mouse germline or cell cultures.
The Postdoctoral Fellow will have opportunities in designing as well as conducting independent projects. New graduates and experienced researchers with a strong record of publications are welcome to apply. An MD, PhD or equivalent degree in a relevant field is required and a strong background in Immunology and/or Molecular Biology is preferred. The ability in initiating, conducting, evaluating and reporting of research studies is essential. Funds available include slots for US citizens / Resident Aliens on a T32 grant and affiliation to the Immunology Training Program.
Further information is available:
http://www.bumc.bu.edu/pulmonary/people/faculty/markus-bosmann-m-d/
Please send your CV, publication list, transcripts and names of three references to:
Markus Bosmann, M.D., Assistant Professor of Medicine, mbosmann@bu.edu
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