招聘简介：
在Tu Dresden，B Cube——分子生物工程中心，分子和细胞生物工程中心（CMCB）的一所研究所，担任分子生物物理（Michael Schlierf教授）主席，担任研究助理/博士后（根据个人资格，员工将根据薪资组E 13 TV-L获得报酬）。从下一个可能的日期开始提供。职位限制为一年，可能延长两年。雇佣期受《固定期限研究合同法》（wissenschaftszeitvertragsgesetz wisszeitvg）管辖。
任务：追踪细胞膜结合细胞器是专门执行特定（生物）化学反应细胞内。然而，细胞器也通过选择性地融合细胞膜来传递和交换其内容物。这种选择性是由于一组专门用于系链细胞膜的特殊蛋白质，使它们更靠近以便随后的融合。一个栓系因子是蛋白质eea1，它通过熵塌陷产生主动拉力（Murray，Jahnel等人自然2016）。我们假设这种崩溃是沿着EEA1的盘绕线圈结构的长距离变构通信的结果。
我们正在寻找一个博士后（生化学家或生物物理学家），以揭示的机制变构螺旋崩溃使用最先进的生化和单分子技术，包括单分子FRET。如有疑问，请联系marino zerial（zerial@mpi-cbg.de或michael schlierf（michael.schlierf@tu dresden.de）。
英文原文：
At TU Dresden, B CUBE – Center for Molecular Bioengineering, an institute of the Center for Molecular and Cellular Bioengineering (CMCB), in the Chair of Molecular Biophysics (Prof. Dr. Michael Schlierf) a position as Research Associate / Postdoc (Subject to personal qualification employees are remunerated according to salary group E 13 TV-L) is available starting at the next possible date.The position is limited for one year with the possibility of an extension of two additional years. The period of employment is governed by the Fixed Term Research Contracts Act (Wissenschaftszeitvertragsgesetz-WissZeitVG).
Tasks: lntracellular membrane-bound organelles are specialized to perform specific (bio)chemical reactions within the cell. However, organelles also communicate and exchange their content by fusing their membranes in a selective fashion. Such selectivity is due to a set of specific proteins that are devoted to tether organelle membranes and bring them closer for subsequent fusion. One tethering factor is the protein EEA1, which generates an active pulling force by an entropic collapse (Murray, Jahnel et al. Nature 2016). We hypothesize that this collapse is the result of a long-range allosteric communication along the coiled-coil structure of EEA1.
We are looking for a postdoc (biochemist or a biophysicist) to reveal the mechanism of the allosteric coiled-coil collapse using state -of-t he-art biochemical and single-molecule techniques, including single-molecule FRET. For questions please contact Marino Zerial (zerial@mpi-cbg.de or Michael Schlierf (michael.schlierf@tu-dresden.de).
Requirements: The position requires a university and PhD degree in biochemistry, biophysics or related fields. The applicant needs to have a profound background in membrane associated proteins and their purification, and the use of state-of-the-art biochemical techniques. Experience with single-molecule techniques is welcome.
Excellent communication skills in English are essential as this is the language at the research centres.
The B CUBE http://www.tu-dresden.de/bcube and MPI CBG http://www.mpi-cbg.de as weil as their partner institutions, the Biotechnology Centre (BIOTEC) and the Center for Regenerative Therapies Dresden (CRTD), are equipped with state-of-the-art facilities for Molecular Bioscience research.
Applications from women are particularly welcome. The same applies to people with disabilities.
Complete applications (letter of motivation, CV, list of publications, and certificates of qualifications) should be sent via the SecureMail Portal of the TU Dresden https://securemail.tu-dresden.de in a single pdf-file to antje.walter1@tu-dresden.de or via mail to TU Dresden, B CUBE, Herrn Prof. Michael Schlierf, Tatzberg 41, 01307 Dresden until 30.04.2019 (stamped arrival date applies). Please submit copies only, as your application will not be returned to you. Expenses incurred in attending interviews cannot be reimbursed.
Reference to data protection: Your data protection rights, the purpose for which your data will be processed, as well as further information about data protect ion is available to you on the website: https://tu-dresden.de/karriere/datenschutzhinweis
为防止简历投递丢失请抄送一份至：boshijob@126.com（邮件标题格式：应聘职位名称+姓名+学历+专业+中国博士人才网）
中国-博士人才网发布
声明提示：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。
