招聘简介：
博士后助理（白血病生物学和表观遗传学）
·迈阿密大学
·地点：佛罗里达州迈阿密
·工作编号：7056858（参考号：R100028319）
·发布日期：2019年4月9日
·申请截止日期：开放至填写
职位描述
迈阿密大学医疗系统和米勒医学院的西尔维斯特综合癌症中心为博士后助理提供了一个激动人心的机会。该职位的重点将是癌症表观遗传学项目，并将在高度协作的环境中研究白血病表观遗传调控和正常造血的分子机制。
我们目前正在寻找一位积极性很高的博士后，具有深入的细胞和分子生物学知识和广泛的技能，以加入实验室。候选人应在各种实验室技术，包括细胞培养和分子生物学分析（分子克隆，细胞增殖分析，亚群体分析）的专业知识。通过facs分析、稳定和短暂的转染、shRNA和病毒结构的使用、DNA和RNA的制备和分析（质粒的制备、常规pcr和rt-pcr）、染色质免疫沉淀（chip）分析、生化分析（elisa、免疫印迹、co-ip）。项目将包括体内和体外候选基因建模，以确定有助于造血恶性肿瘤发展的表观遗传沉默基因，并利用体内和体外系统对候选基因进行表征。
英文原文：
Postdoctoral Associate (Leukemia Biology and Epigenetics)
· University of Miami
· Location: Miami, FL
· Job Number: 7056858 (Ref #: R100028319)
· Posting Date: Apr 9, 2019
· Application Deadline: Open Until Filled
Job Description
The Sylvester Comprehensive Cancer Center with the University of Miami Health System and Miller School of Medicine has an exciting opportunity for a Postdoctoral Associate. The focus of this position will be in the Cancer Epigenetics Program and will work in a highly collaborative environment investigating the molecular mechanisms of epigenetic regulation of leukemia and normal hematopoiesis.
We are currently seeking a highly motivated Postdoctoral Associate with in-depth knowledge and extensive skills in cellular and molecular biology to join the lab. The candidates should demonstrate expertise in various lab techniques including cell culture and molecular biology assays (molecular cloning, cell proliferation assay, subpopulation analysis by FACS, stable and transient transfection, use of shRNA and viral constructs), preparation and analysis of DNA and RNA (preparation of plasmids, regular PCR and RT-PCR), chromatin immunoprecipitation (ChIP) assays, biochemical assays (ELISA, immunoblotting, Co-IP). Projects will include in vivo and in vitro modeling of candidate genes to identify epigenetically silenced genes that contribute to the development of hematopoietic malignancies and characterization of candidate genes using in vitro and in vivo systems.
Minimum Qualifications
Ph.D. or other doctoral-level degree in a relevant field of study, or M.D. Strong molecular biology or cancer biology skills. Previous experience with epigenetics, cancer modeling or hematopoiesis is preferred. Evidence of scholarly ability (record of publication in peer-reviewed journals, etc.) must be presented. Ability to communicate in written and spoken English is required. It is expected that the candidate will have the ability to work independently, design experiments with appropriate controls, collect and tabulate data, publish and present results, as well as to participate in the training of graduate and rotation students in a research laboratory setting.
UHealth-University of Miami Health System, South Florida's only university-based health system, provides leading-edge patient care powered by the ground breaking research and medical education at the Miller School of Medicine. As an academic medical center, we are proud to serve South Florida, Latin America and the Caribbean. Our physicians represent more than 100 specialties and sub-specialties, and have more than one million patient encounters each year. Our tradition of excellence has earned worldwide recognition for outstanding teaching, research and patient care. We're the challenge you've been looking for.
Patient safety is a top priority. As a result, during the Influenza ("the flu") season (September through April), the University of Miami School of Medicine requires all employees who provide ongoing services to patients, work in a location (all Hospitals and clinics) where patient care is provided, or work in patient care or clinical care areas, to have an annual influenza vaccination. Failure to meet this requirement will result in rescinding or termination of employment.
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