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美国斯克里普斯研究所(TSRI)-斯克里普斯佛罗里达大学博士后职位

时间:2019-04-23来源:中国博士人才网 作者:佚名

 招聘简介:

  斯克里普斯研究所(TSRI)是世界上最大的独立非营利研究机构之一,站在基础生物医学科学的前沿,这是医学研究的一个重要部分,旨在了解生命的最基本过程。

  我们目前正在寻找(2)个博士后助理职位,在高级科学主任蒂姆·斯派克的实验室工作。理想的候选人将获得生物学、化学或工程学博士学位。成功的候选人将负责早期药物发现倡议,重点关注功能性和靶向性方法,利用各种细胞和生化高通量筛选(HTS)药物发现分析技术调节疾病生物学。这一机会是为寻求在工业规模HTS和与制药行业相关的程序方面接受高级技能培训的个人提供的。成功的候选人将负责开发和优化各种化验,并在全自动HTS平台上进行筛选。重点将包括三维组织培养模型,ipsc标度和诱导筛选生理相关的人体模型。熟练操作常用的实验室和分析设备,能与多台平板读出器和细胞培养一起工作将是主要优势。在酶动力学、高含量成像、3D组织培养、CRISPR和IPSCS方面有丰富的背景也将是一个优势。应聘者必须具备良好的沟通能力,并希望能在一个快速、多学科的合作团队中工作。

  英文原文:

  The Scripps Research Institute (TSRI), one of the world’s largest independent non-profit research facilities, stands at the forefront of basic biomedical science, a vital segment of medical research that seeks to comprehend the most fundamental processes of life.

  We are currently seeking (2) Postdoctoral Associate positions to work within the Laboratory of Senior Scientific Director Tim Spicer. The ideal candidates will have a Ph.D. in Biology, Chemistry or Engineering. The successful candidates will be responsible for early drug discovery initiatives focusing on functional and target-based approaches to modulate disease biology using a variety of cell based and biochemical high-throughput screening (HTS) drug-discovery assay techniques. This opportunity is for individuals seeking to be trained in advanced skills for industrial scale HTS and procedures relevant to the pharmaceutical industry. The successful candidates will be responsible to develop and optimize a variety of assays and implement them for screening on a fully automated HTS platform. Focus will include 3D tissue culture models, iPSC scaling and induction for screening in physiologically relevant human models. Proficiency with operation of common laboratory and analytical equipment and ability to work with multiple plate readers and cell culture would be a major advantage. Proven background in enzyme kinetics, high content imaging, 3D tissue culture, CRISPR and iPSCs would also be an advantage. Candidates must have excellent communication skills and desire to work in a fast paced, multi-disciplinary collaborative team.

  To learn more about this position please visit our website. In order to be considered for a position, you must apply through the job postings: Requisition Number: 06688 and Requisition Number: 06689

  Join a world leader in the discovery and early application of biomedical breakthroughs for human health. Together we can make a difference.

  The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.

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