丹麦哥本哈根大学健康与医学学院肥胖研究体内外药理学项目博士后职位

Department of Veterinary and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, wishes to appoint a talented post doc for a 2-year position for a joint in vivo/in vitro pharmacology project in obesity research from 15 November 2020 or as soon as possible hereafter.

The Faculty of Health and Medical Sciences and Novo Nordisk A/S did in 2010 jointly establish a research centre – The LIFEPHARM Centre – with a total budget of DKK 140 mill covering activities until the end of 2023. The present position is part of the Centre’s activities. The purpose of the research centre is to strengthen the research in experimental pharmacology and toxicology and to increase the output of postdocs and PhDs with a strong in vivo pharmacological profile. It is expected that the future post doc will actively participate in and support the Centre’s activities. For further information on the Centre see www. lifepharm.dk

Project description

As a collaboration between part of Obesity Biology Department at Novo Nordisk and LifePharm, this project is focused on identifying new pathogenetic mechanisms in weight maintenance problems and novel strategies in obesity management. The project is directed towards the role of hypothalamo-pituitary- adrenal axis in regulation of energy expenditure and potential therapeutic targets within this system. A large part of the project is centred on animal experiments, in vivo metabolic assessment and development of an in vitro platform to validate and perform in vitro assays and mode-of-action studies.

Principal supervisor Professor Jens Lykkesfeldt E-mail: jopl@sund.ku.dk

Direct Phone: (+45) 35 33 31 63 Faculty of Health and Medical Sciences University of Copenhagen

Project supervisor

Natalia Petersen, MSc, PhD, Novo Nordisk; napt@novonordisk.com; phone 60577206

Job description

We are looking for a particularly skilled candidate who can bridge the physiological parameters and signalling pathways in the HPA axis. We seek an individual with extensive knowledge of rodent metabolic tests, in vitro and ex-vivo assays/models related to neuroendocrinology and hormone secretion. The candidate will be responsible for executing all parts of the project, with a particular focus on the design of experiments. The laboratory work will be located both in vivo and in vitro Obesity departments at Novo Nordisk. There is a possibility to establish a collaborations network within this project. While the post doc’s main duties will be research within the above-mentioned project, the position may also include some teaching/supervisory obligations.

Qualification requirements

In connection with the appointment to the post special importance will be attached to the applicant having the professional and personal qualifications stated below:

  Documented scientific qualifications as PhD or equivalent within cell biology, pharmacology, biomedicine or similar disciplines

  A documented scientific track record and in-depth knowledge of hormone biology and neuroendocrine systems

  Documented experience with rodent handling and metabolic phenotyping

  Supervisor/teaching skills

  Fluency in English. University of Copenhagen generally encourages employees who do not speak Danish to acquire a working knowledge of the language

Additional preferred skills and experiences:

  Experience establishing primary neuronal cultures, pituitary gland isolation from mice and rats organoid culture, multi-cell co-culture

  Experience with energy expenditure studies

  Experience with hormone assays, calcium measurements, gene expression analysis, microscopy and imaging, immunohistochemistry and pharmacology testing.

The candidate will take an advantage in in vivo pharmacology training based in Novo and we expect her/him to contribute with knowledge on neuron and pituitary gland field and in vitro work. On the personal level, we are looking for a result-oriented, thorough and innovative candidate with good collaboration and problem-solving skills.

Terms of employment

Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organisations. The position is covered by the Job Structure for Academic Staff at Universities (2020).

Questions

For further information about the post, please contact Jens Lykkesfeldt (phone 35333163, jopl@sund.ku.dk) or Natalia Petersen (phone 60577206, napt@novonordisk.com).

Foreign applicants may find the following links useful: www. ism.ku.dk (International Staff Mobility) and www. workingconditions.ku.dk

Application

The application must be submitted in English, by clicking on “Apply online” below, and must include the following:

  Application detailing the basis on which the applicant wishes his or her scientific, teaching and other qualifications to be assessed

  Curriculum vitae

  Diplomas – all relevant certificates

  A complete list of publications

  A maximum of 10 relevant scientific works which the applicant wishes to be included in the assessment

  Documentation for additional research qualifications

  Teaching portfolio:

  Participation in development of educations and seminars

  Development of educational material

  Experience with examination and/or censorship

Please note that the applicant will be contacted if the assessment committee requires further documentation.

The application will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen encourages all interested in this post to apply.

Please submit the application with the required attachments by clicking on “Apply online” below. Only online applications will be accepted.

The closing date for applications is 13 September 2020.

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