Research Fellow - Post-transcriptional Control of Gene Expression : Guildford, United Kingdom

Salary: £29,541 per annum
Duration: up to 36 months
Start date: available immediately

A Postdoctoral position is available in the group of Prof. André Gerber to investigate combinatorial control of gene expression by RNA-binding proteins and non-coding RNAs (for review see Imig et al. 2012 BioMol. Concepts, 3, 403). The project is funded by the BBSRC for up to 3 years.

The aim of the project is to investigate how combinatorial arrangement of proteins/ncRNAs affects the fate of selected mRNAs during stress and in cancer. It involves the application and further development of a new method for biochemical purification of stress and cancer-related RNAs from yeast and human cancer cells, respectively, followed by the systematic identification of the bound proteins/ncRNAs with proteomics/genomics means. You will be expected to combine transcriptomics (e.g. RNA-Seq, microarrays) and proteomics with classical biochemical, genetic and cell-biological methods.

You will be an excellent and highly motivated scientist with a Ph.D. in biochemistry, molecular biology or related field. Previous experience with genomics and/or proteomics tools and bioinformatics/computational biology would be a great plus. Good communication skills are essential. You will also be expected to participate in national and international collaborations.

Our benefits package includes generous annual leave, final salary pension scheme, relocation provision, childcare assistance and leisure facilities.

Closing date: Wednesday 29th May 2013

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