Postdoctoral position

Research Area: Myotonic dystrophy/Small molecule therapy

Expression of expanded CUG repeat RNA plays a central role in the development of myotonic dystrophy pathology.

We have developed novel RNA screens to identify small molecule therapeutics that selectively inactivate toxic CUG repeat RNAs. Our approach also has relevance for the development of therapeutics directed against RNA targets in other diseases.

We are seeking a highly motivated post-doctoral candidate to use these approaches to identify novel therapeutics for myotonic dystrophy and study their mechanism of action in patient cells and mouse models.

Experience in molecular biology, biochemistry or medicinal chemistry is required. Experience in RNA biology is desirable. 100% grant funded. Contract renewable based on performance.

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