奥地利维也纳生物中心2025年博士后招聘（核膜作为智能边界）
Two Postdoctoral Positions – Nuclear Envelope as an Intelligent Boundary
Employer
Köhler Lab, Max Perutz Labs
Location
Vienna BioCenter, Austria
Salary
欧元69,000+ per annum (adjustable based on experience)
Closing date
20 Aug 2025
Köhler Lab, Max Perutz Labs, Vienna BioCenter
Rethinking cellular boundaries
Cellular boundaries are not passive—they are interfaces that convert spatial separation into function. Membranes, nuclear pores, and phase boundaries establish localized environments that concentrate activity, enhance specificity, and scaffold complex regulation. These interfaces don't just divide—they integrate: shaping interactions and encoding control in space and time.
The nuclear envelope exemplifies this principle. Far from a static shell, it is an intelligent boundary—an adaptive interface, not in a cognitive sense, but in its capacity to integrate genome organization, lipid metabolism, transport, and translation across nuclear and cytoplasmic domains.
The Köhler Lab invites applications for two fully funded postdoctoral positions in nuclear envelope biology and cellular stress resilience. These roles offer a unique opportunity to pursue ambitious, long-term research in a rigorous, idea-driven environment at one of Europe’s leading life science hubs.
Both positions may transition into permanent research appointments, depending on scientific vision and contribution. The position offers a minimal annual salary of 欧元 69,000 and is adjustable based on research experience.
Research Focus
Our work centers on the nuclear envelope—a hallmark of eukaryotic evolution that integrates mechanical resilience, selective transport, lipid metabolism, and gene regulation. We investigate:
Lipid metabolism of the nuclear envelope
Nuclear pore complex architecture
Chromatin-associated signaling pathways
As one of our model systems, we use tardigrades—the toughest animals on Earth. Tardigrades’ resilience to desiccation, radiation, and temperature offers a unique opportunity to explore the limits at which cellular boundaries can operate.
Our approach
We combine biochemical reconstitution, live-cell imaging, multi-scale structural biology, and omics technologies to uncover how the nuclear envelope functions as an intelligent boundary between nuclear and cytoplasmic domains—even under extreme stress.
Recent Contributions
Lipid metabolism at the inner nuclear membrane shapes nuclear architecture
Romanauska & Köhler, Cell 2018
Phase-separated chromatin compartments for ubiquitin signaling
Gallego et al., Nature 2020
Reconstitution of the nuclear pore basket on synthetic membranes
Stankunas & Köhler, Nature Cell Biol. 2024
Engineering nuclear envelope geometries to probe lipid chemistry-function relationships
Romanauska & Köhler, Nature Cell Biol. 2023
What We Offer
Two fully funded, full-time postdoctoral positions
Possibility of transitioning to a permanent research role
Freedom to develop independent ideas within a clear and ambitious research program
Strong institutional and grant support
Access to advanced technologies: cryo-EM, imaging, proteomics, and other core facilities
A collaborative, conceptually driven lab culture
Candidate Profile
We are looking for researchers with:
A PhD in molecular biology, cell biology, biochemistry, biophysics, or a related field
Interest in membrane biology, chromatin regulation, stress resilience, or non-model organisms
Experience in biochemical reconstitution, imaging, or omics-based approaches
Intellectual curiosity, precision, and the motivation to contribute lasting insights to fundamental biology
Scientific Environment
The Max Perutz Labs (https://www.maxperutzlabs.ac.at) are part of the Vienna BioCenter (https://www.viennabiocenter.org), a major European life science campus with over 50 research groups and world-class infrastructure.
Located in Vienna—a city known for its exceptional quality of life—we benefit from robust funding and a vibrant international scientific community. English is the working language across the campus.
How to Apply
Please send your CV, a statement of research interest, and contact information for two referees to: alwin.koehler@maxperutzlabs.ac.at
Review of applications will begin immediately and continue until the positions are filled. Early applications are encouraged.
Lab website: https://www.maxperutzlabs.ac.at/research/research-groups/koehler
为防止简历投递丢失请抄送一份至：boshijob@126.com（邮件标题格式：应聘职位名称+姓名+学历+专业+中国博士人才网）
中国-博士人才网发布
声明提示：凡本网注明“来源：XXX”的文/图等稿件，本网转载出于传递更多信息及方便产业探讨之目的，并不意味着本站赞同其观点或证实其内容的真实性，文章内容仅供参考。
