Postdoctoral Researcher (f/m/d) or PhD studend (f/m/d)
German Center for Neurodegenerative Diseases (DZNE)
The German Center for Neurodegenerative Diseases (DZNE) is a unique non-university research center which is dedicated to the subject dementia and all its areas, as well as other neurodegenerative diseases. The center compasses the full spectrum of fundamental research through population sciences to health care research. The DZNE stands for excellence in research and science management, translation of scientific results into practice, interdisciplinarity and internationalization. It is a research center within the Helmholtz Organization of German research centers. With over 1,000 employees from 55 nations, spread over 10 sites, the DZNE is one of the national and international leading research centers in its research field.
The DZNE in Bonn is looking for a
Postdoctoral researcher (f/m/d)
PhD student (f/m/d)
The Neurovascular Diseases Research Group (PI: Gabor Petzold) is interested in the pathogenesis of stroke, vascular dementia and neurodegenerative diseases, with a particular focus on glial cells and vascular factors contributing to cognitive decline. We use techniques such as in vivo two-photon microscopy, ischemia models, electrophysiology, whole-brain clearing techniques, small-animal MRI, and behavioral assessment. We possess, or have unlimited access to, state-of-the-art equipment and facilities.
For this position funded by the German Research Foundation (DFG), we aim to investigate the role of astroglial and neuronal glutamate homoeostasis in animal models of stroke, based on our previous work (e.g., J Clin Invest 2017). Techniques used in this project will include in vivo calcium and glutamate imaging using genetically engineered fluorescent indicators, focal ischemia, transgenic manipulation, chronic drug administration and behavioral assessment.