从事生物分析传感、微流控及现场快速检测(point-of-care testing)的研究,以及相关产品的研发。
有意者请发简历至:liuh@seu.edu.cn(邮件标题注明:应聘岗位+毕业院校+本人姓名)
刘宏,教授,博士生导师,2014年入选国家“人才”青年项目,以及江苏省“双创人才”,2014年共获得各类研究经费近500万元。
个人主页:www.liuhong.info
2006年毕业于南京大学,获理学学士学位。2009年毕业于南京大学,获理学硕士学位。2012年毕业于美国德克萨斯大学奥斯汀分校,获哲学博士(PhD)学位,2012-2013年,美国德克萨斯大学奥斯汀分校博士后,2013年至今就职于东南大学生物科学与医学工程学院,生物电子学国家重点实验室。曾在美国作为核心研究人员参与了3 项由美国国防部资助的科研项目,在国际上较早地开展了纸微流控分析芯片的研究,在三维纸微流芯片和传感器信号转换与放大方法的研究中,处于国际领先水平。发明的纸微流控芯片被美国国立健康研究院NIH的Stetten博物馆作为一个里程碑式的发明永久收藏。在Angew. Chem. Int. Ed., J. Am. Chem. Soc.等重要杂志上共发表SCI 论文15 篇(第一作者8 篇),申请美国专利4项,国家发明专利2项。论文影响因子之和为101.744(第一作者影响因子之和为58.583)。影响因子最低为5.695,最高为13.734。论文被引用约400多次,被Nature Materials,Chemical Reviews等数百个杂志报道。
部分论文:
1. Liu, H. and Crooks, R. M. “Determination of percent hemoglobin a
2. Liu, H. Li, X. and Crooks, R. M. Paper-Based SlipPAD for High-Throughput Multiplexed Chemical Sensing. Anal. Chem. 2013, 85, 4263−4267.
3. Liu, H. Xiang, Y.; Lu, Y. and Crooks, R. M. “Aptamer-based origami paper analytical device for electrochemical detection of adenosine”, Angew. Chem. Int. Ed. 2012, 51, 6925-6928.
4. Liu, H. and Crooks, R. M. “A paper-based electrochemical sensing platform with integral battery and electrochromic read-out”, Anal. Chem. 2012, 84, 2528−2532.
5. Liu, H. and Crooks, R. M. “Three-dimensional paper microfluidic devices assembled using the principles of origami”, J. Am. Chem. Soc. 2011, 133, 17564-17566. highlighted on Nature Materials, Lab Chip, C&EN news, R&D Magazine etc. An online slideshow for the oPAD story (http://web3.cns.utexas.edu/slideshows/oPAD/)
6. Liu, H. and Crooks, R. M. “Highly reproducible chronoamperometric analysis in microdroplets.” Lab Chip 2013, 13, 1364-1370.
7. Liu, H.; Yang, Z. J.; Yan, F.; Xu, Y. M. and Ju, H. X. “Three-minute-long chemiluminescent immunoassay using dually accelerated immunoreaction by infrared heating and passive mixing”, Anal. Chem. 2009, 81, 4043-4047.
8. Liu, H.; Fu, Z. F.; Yang, Z. J.; Yan, F. and Ju, H. X. “Sampling-resolution strategy for one-way multiplexed immunoassay with sequential chemiluminescent detection”, Anal. Chem. 2008, 80, 5654-5659.
9. Yang, Z. J.; Liu, H.; Zong, C; Yan, F. and Ju, H. X. “Automated support-resolution strategy for a one-way chemiluminescent multiplex immunoassay”, Anal. Chem. 2009, 81, 5484-5489.
10. Yang, Z. J.; Fu, Z. F.; Yan, F.; Liu, H. and Ju, H. X. “A chemiluminescent immunosensor based on antibody immobilized carboxylic resin beads coupled with micro-bubble accelerated immunoreaction for fast flow-injection immunoassay”, Biosens. Bioelectron. 2008, 24, 35-40.
11. Fu, Z. F.; Yan, F.; Liu, H.; Lin, J. H. and Ju, H. X. “A channel-resolved approach coupled with magnet-captured technique for multianalyte chemiluminescent immunoassay”, Biosens. Bioelectron. 2008, 23, 1422-1428.
12. Fu, Z. F.; Yan, F.; Liu, H.; Yang, Z. J. and Ju, H. X. “Channel-resolved multianalyte immunosensing system for flow-through chemiluminescent detection of α-fetoprotein and carcinoembryonic antigen”, Biosens. Bioelectron. 2008, 23, 1063-1069.
13. Fu, Z. F.; Yang, Z. J.; Tang, J. H; Liu, H.; Yan, F. and Ju, H. X. “Channel and substrate zone two-dimensional resolution for chemiluminescent multiplex immunoassay”, Anal. Chem. 2007, 79, 7376-7382.
14. Fu, Z. F.; Liu, H. and Ju, H. X. “Flow-through multianalyte chemiluminescent immunosensing system with designed substrate zone-resolved technique for sequential detection of tumor markers”, Anal. Chem. 2006, 78, 6999-7005.
15. Yang, Z. J.; Xie, Z. Y.; Liu, H.; Yan, F. and Ju, H. X. “Streptavidin-functionalized three-dimensional ordered nanoporous silica film for highly efficient chemiluminescent immunosensing”, Adv. Funct. Mater. 2008, 18, 1-8.
16. Fu, Z. F.; Liu, H.; Yang, Z. J. and Ju, H. X. “Recent developments in multianalyte immunoassay”, Current Trends Biotechnol. Pharm. 2007, 1, 1-17.
已申请专利:
1. Crooks, R. M.; Liu, H.; Villwock, R. D.; Scida, K.; Renault, C. and Bohn, P. “Method for the detection and quantification of analytes using three-dimensional paper-based devices”, US Patent Application, 13/865,352, April 18, 2013.
2. Crooks, R. M.; Liu, H.; Villwock, R. D.; Scida, K.; Renault, C. and Bohn, P. “Method for the detection and quantification of antibodies”, 61/756,772, Jan 25, 2013.
3. Crooks, R. M. and Liu, H. “3-D sensing systems fabricated by paper folding”, US Patent Application, 61/641,880, May 2 2012.
4. Crooks, R. M. and Liu, H. “3-D fluidic analytical device fabricated by paper folding”, US Patent Application, 61/635,081, Apr. 18 2012.
5. Yan, F.; Liu, H. and Ju, H. X. “Rapid chemiluminescent immunoassay system and analytical method”, 国家发明专利, 200910029449.X.
6. Yan, F.; Liu, H. and Ju, H. X. “Automated sampling-resolution chemiluminescent multiplexed immunoassay system and analytical method”, 国家发明专利, 200810024426.5.
东南大学是中央直管、教育部直属的全国重点大学,是“985工程”和“211工程”重点建设的大学之一。学校坐落于历史文化名城南京,占地面积5880亩,建有四牌楼、九龙湖、丁家桥等校区。东南大学是我国最早建立的高等学府之一,素有“学府圣地”和“东南学府第一流”之美誉。东南大学前身是创建于1902年的三江师范学堂。1921年经近代著名教育
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