Postdoctoral Fellowship in Immunity and Cancer
Immunity and Cancer Laboratory
Cancer Research UK / London Research Institute
Full time, 4 years Fixed Term
Competitive salary
Closing date: 16th July 2013

A postdoctoral position is available at Dinis Calado’s Lab at the Cancer Research UK / London Research Institute, in London, United Kingdom. The Lab performs integrative studies on immunology and cancer biology to understand how healthy cells become cancerous, using mainly B-lymphocytes as model system.

Proposed projects aim to:
• Identify and study subpopulations within healthy cells at a particularly high risk of becoming cancer cells, i.e. “cells of origin in cancer”.
• Investigate the causative mutations, including the study of non-coding RNAs responsible for cancer development and progression.
• Assess the processes of evasion of cancer cells from immune control by determining the nature of the interplay between a developing cancer and the cells of the immune system.

To address these questions the Lab has in place cutting-edge genetic techniques in vivo in the mouse, and performs mouse I human inter-species comparisons to confirm and/or validate the results obtained in the mouse system.

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