POSTDOCTORAL POSITIONS: REPRODUCTIVE SYSTEMS BIOLOGY
The Krawetz group http://compbio.med.wayne.edu is using the human protamine gene cluster, as a model of chromatin mediated genome reprogramming and RNA delivery by sperm to understand early human development.
See:
Linnemann, A.K., Platts, A.E., Doggett, N., Gluch, A., Bode, J. and Krawetz S. A. (2007) Genome wide identification of nuclear matrix attachment regions: an analysis of methods. Biochemical Society Transactions. 35:612-617.
Martins, R. P. and Krawetz, S.A. (2007) Decondensing the protamine domain for transcription. Proceedings of the National Academy of Sciences (U.S.A.) 104:8340-8345.
Krawetz, S.A. (2005) Paternal Contribution: new insights and future challenges. Nature Reviews Genetics 6:633-642.
Platts, A.E., Dix, D. J., Chemes, H.E., Thompson, K.E., Goodrich, R., Rockett, J. C., Rawe, V.Y., Quintana, S., Diamond, M.P., Strader, L.F. and Krawetz, S.A. (2007) Success and failure in human spermatogenesis as revealed by teratozoospermic RNAs. Human Molecular Genetics. 16:763-773.
As part of an interdisciplinary research team using advanced HTGS, CGH, FISH, Microarray, Real-Time and Computational technologies we will determine how chromatin structure and RNA are used to reprogram our genome. Self motivated individuals trained in molecular biology, genetics, cytogenetics and/or biochemistry with expertise in HTGS, CGH, FISH and MICROARRAYS are especially encouraged to apply.
Applicants should forward their cv and three letters of reference to: Dr. S. A. Krawetz, C.S. Mott Center for Human Growth and Development, Wayne State University School of Medicine, 275 E. Hancock, Detroit, MI 48201.
E-mail: steve@compbio.med.wayne.edu.
WSU is an Equal Opportunity/Affirmative Action Employer.
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