Postdoctoral Fellow position in the Neurobiology of Addiction Research Center (NARC) at the Medical Univ of South Carolina available immediately. The primary goal of the NARC is to use animal models to identify the neurobiological basis of why addicts’ motivation to obtain addictive drugs is so great and why their ability to develop behaviors that compete with drug seeking and use is impaired. By probing the molecular basis of how cocaine changes the brain, investigators are determining which of the proteins that regulate communication between nerve cells are most greatly affected in rats trained to self-administer cocaine. The next stage of research in the NARC is to use rat models of relapse to determine if normalizing the proteins and physiological processes affected by cocaine can prevent cocaine relapse in translational studies. The selected candidate will be trained in traditional behavioral (drug self administration) and cellular-molecular (gene, protein analysis) approaches as well as in the use of cutting-edge tools (optogenetics, in vivo viral-vector delivery, DREADDs).
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