Postdoctoral position in MS-based proteomics

 
Employer:  University of Copenhagen  

Date Posted:  10/06/2014  
Application Deadline: 10/31/2014 

 
Job Description

One postdoctoral stipend is available in the Proteomics Technology Development & Application group at The Novo Nordisk Foundation Center for Protein Research (CPR – www.cpr.ku.dk). The Center has been established at the Faculty of Health and Medical Sciences, University of Copenhagen, to promote basic and applied discovery research on human proteins of medical relevance. The Center comprises a wide range of expertise and resources including proteomics, protein production and characterization to disease mechanisms. The proteomics section is headed by Prof. Dr. Matthias Mann, and the “Proteomics Technology Development & Application” group is lead by Group Leader Dr. Michael L. Nielsen. By joining our team, you will be part of a young and dynamic team consisting of international researchers. The Nielsen group focuses on developing novel proteomics methods & technologies for studying the cellular outcomes at a ‘systems-level’, with the aim to understand cellular phenotypes and diseases. To this end, we employ cutting-edge mass spectrometry (MS)-based technologies for developing unbiased proteomics methods for identification and quantification of post-translational modifications (PTMs), such as ubiquitylation, arginine methylation and ADP-ribosylation (Danielsen et al, MCP, 2011; Sylvestersen et al, COCB, 2013; Sylvestersen et al, MCP, 2014; Jungmichel et al, Mol Cell, 2013) and other cellular signalling molecules like phophoinositides (Jungmichel et al, Cell Reports, 2014).

For more information about the research group please visit:
http://www.cpr.ku.dk/research/proteomics/proteomics-technology-development--application/

If you still have questions, contact us: jobs@cpr.ku.dk.

Project Description
Recently, we have improved mass spectrometry-based proteomics methods for unbiased analysis of various post-translational modifications (Jungmichel et al, Mol Cell., 2013; Sylvestersen et al, MCP, 2014; Tessarz et al, Nature, 2014; Christophorou et al, Nature, 2014). The applicant is expected to use cutting-edge proteomic technology for characterization of post-translational modifications in mammalian cell systems, and to perform biological follow-up experiments on novel and interesting findings derived from these proteomic screens. However, candidates interested in developing novel proteomic technologies are also encouraged to apply. The ideal candidate should be able to conduct independent and creative research, demonstrate scientific productivity, and show good inter-personal and communication skills.

Projected start date: Fall 2014/Spring 2015 or later.

Qualifications

The candidate is required to have PhD or equivalent degree in natural or medical science.
Excellent scientific track record, including at least one publication as first author in a high quality, peer reviewed international journal.
Prior experience in research fields related to post-translational modifications, such as poly-ADP-ribosylation, arginine methylation, or othes would be considered a distinct advantage.
Prior experience in high resolution mass spectrometry is not essential, but would be considered an advantage.
Good communication skills, both oral and written.
An analytical aptitude for devising innovative scientific or technical solutions.
Demonstrate enthusiasm, motivation, flexibility and confidence.

Place of employment and work
The employment is at CPR (www.cpr.ku.dk), University of Copenhagen, located in central Copenhagen. The research environment at CPR is vibrant, ambitious, and international, with approx. 30 different nationalities currently represented. The Center comprises modern laboratories and state-of-the-art facilities within protein science. Seminars with high-profile international speakers and regular internal research seminars are organized at the Center.

Terms of salary and employment
Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary is around 31,800 – 33,500 DKK (around 4,250€) plus 17.1 % in pension contribution.

Application
Your application should be submitted electronically to the link below in this advertisement:

or through: http://ssl1.peoplexs.com/Peoplexs22/CandidatesPortalNoLogin/ApplicationForm.cfm?PortalID=12921&VacatureID=691308

Your application should include the following documents:

Motivated letter of application
Curriculum vitae, incl. education and experience
List of publications
Letters of recommendation
Names and contact details for two referees
For further information about the position, please contact Group Leader Michael Lund Nielsen Michael.lund.nielsen@cpr.ku.dk

Deadline for application: 31 October 2014  
 
   
  
Contact:  Michael Lund Nielsen 
Proteomics Technology Development & Application group at The Novo Nordisk Foundation Center for Protein Research
University of Copenhagen
Copenhagen,  2200
Denmark  
Online Application: Apply for this job from Employer's website 
 
 基于MS的蛋白质组学博士后

 
雇主：哥本哈根大学 

发布日期：2014年10月6日 
报名截止日期：2014年10月31日

 
职位描述

一个博士后津贴是蛋白质组学技术开发与应用组的诺和诺德基金会中心蛋白质研究可用（CPR - www.cpr.ku.dk）。该中心成立至今，在卫生和医学科学，哥本哈根大学的学院，以促进医疗相关的人体蛋白质的基础和应用开发研究。该中心包括一个广泛的专业知识和资源，包括蛋白质组学，蛋白质的生产和表征疾病的机制。蛋白质组学部分由教授马蒂亚斯·曼恩博士为首，而“蛋白质组学技术开发与应用”组中的主角由组长博士迈克尔·L.尼尔森。加入我们的团队，你将是一个年轻而充满活力的团队组成的国际研究的一部分。尼尔森集团专注于开发新的蛋白组学方法与技术研究细胞的成果，在一个“系统级”，目的是了解细胞表型和疾病。为此，我们采用尖端的质谱（MS）为基础的技术的发展不偏不倚蛋白质组学方法鉴定的翻译后修饰（翻译后修饰），如泛素，精氨酸甲基化和ADP-核糖基化（丹尼尔森等和量化， MCP，2011; Sylvestersen等，COCB，2013; Sylvestersen等，MCP，2014年; Jungmichel等，分子细胞，2013年）和其他细胞信号分子如phophoinositides（Jungmichel等，细胞报道，2014年）。

有关调研组的更多信息，请访问： 
http://www.cpr.ku.dk/research/proteomics/proteomics技术开发 - application/

如果您还有疑问，请联系我们：jobs@cpr.ku.dk。

项目简介 
最近，我们又提高了质谱为基础的蛋白质组学方法对各种翻译后修饰公正的分析（Jungmichel等，分子细胞，2013; Sylvestersen等，MCP，2014年; Tessarz等，Nature，2014年; Christophorou等自然，2014年）。申请人预计使用尖端的蛋白质组学技术用于在哺乳动物细胞系统中的翻译后修饰的表征，并且对从这些蛋白质的屏幕衍生的新的和有趣的发现执行生物后续实验。但是，我们也鼓励有兴趣发展的新技术，蛋白质组学候选人申请。理想的候选人应该能够进行独立和创造性的研究，展示了科学的生产效率，并表现出良好的人际关系和沟通技巧。

预计开始日期：2014年秋季/春季2015年或以后。

资格

应聘者须具有博士学位或同等学历，在自然或医学。 
优秀的研发背景，包括至少一个出版物作为第一作者的一种高品质，同行评审国际期刊。 
在与翻译后修饰研究领域，如聚ADP-核糖基化，甲基化精氨酸，或othes以前的经验将被视为一个明显的优势。 
在高分辨质谱现有经验不是必需的，但是将被认为是一个优点。 
良好的沟通能力，口头和书面。 
一个分析能力倾向，以便制订创新的科学或技术解决方案。 
展现热情，积极性，灵活性和信心。

就业和工作场所 
就业是心肺复苏术（www.cpr.ku.dk），哥本哈根大学，位于哥本哈根市中心。在心肺复苏的研究环境是充满活力的，有事业心，以及国际，与约目前，代表30个不同的国籍。该中心包括蛋白质科学中的现代化的实验室和国家的最先进的设施。研讨会与高知名度的国际演讲者和定期的内部研究讨论会的组织为中心。

条款的工资和就业 
工资，养老金和就业方面将按照财政部和学者中央组织之间的协议。目前，月薪约31,800 - 33,500丹麦克朗（约4,250€）的抚恤金，另加贡献17.1％。

应用 
您的应用程序应以电子提交下面这则广告的链接：

或者通过： http://ssl1.peoplexs.com/Peoplexs22/CandidatesPortalNoLogin/ApplicationForm.cfm?PortalID=12921&VacatureID=691308

您的应用程序应该包括下列文件：

申请动机信 
履历，包括教育和经验 
出版物清单 
推荐信 
姓名和联系方式，有两个裁判 
有关位置的详细信息，请联系集团负责人迈克尔·隆德尼尔森Michael.lund.nielsen@cpr.ku.dk

申请截止日期：2014年10月31日 
 
   
  
联系方式：迈克尔·尼尔森隆德 
蛋白质组学技术开发与应用组的诺和诺德基金会中心蛋白质研究 
哥本哈根大学 
哥本哈根，2200 
丹麦 

为防止简历投递丢失请抄送一份至：boshijob@126.com（邮件标题格式：应聘职位名称+姓名+学历+专业+中国博士人才网）