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美国纪念斯隆凯特林癌症中心招收博后

时间:2016-04-08来源:未知 作者:91boshi

Post-doctoral Fellow – Cancer Research : New York, United States

Postdoctoral fellow position is available immediately in a multidisciplinary team composed of chemists and biologists. The goal of our investigational program is to study the nature of chronic stress as it occurs in numerous diseases and aging; we use this knowledge for the discovery and clinical translation of diagnostics and therapeutics.

For publications relevant to this position please refer to:
Cell Rep. 2015 Dec 15;13(10):2159-73; A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species.
J Clin Invest. 2015 Nov 3;125(12):4559-71; Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma.
Blood. 2014 Mar 27;123(13):2075-83; Improved targeting of JAK2 leads to increased therapeutic efficacy in myeloproliferative neoplasms.
Nat Chem Biol. 2013 Nov;9(11):677-84; Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2.
Nat Chem Biol. 2011 Sep 25;7(11):818-26; Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90.

Open positions: 
Cell biology / Tumor biology / Biochemistry: to inquire into mechanisms associated with chaperones in disease; investigate modalities for the optimal translation of chaperone inhibitors to the treatment of cancers. These efforts will be conducted in collaboration with scientists and clinicians at Memorial Sloan Kettering Cancer Center, Weill Cornell Medical College and Medical University of South Carolina.

The successful candidate will:
• Have up to five years of postdoctoral experience with a demonstrated competence and experience in the biology of cancer. 
• Have demonstrated ability to work independently and lead projects while also collaborating and assisting the group achieve its research goals

Candidates with an ability to interact well with a large interdisciplinary team are encouraged to apply.

Requirements:
• A strong desire to impact cancers 
• Creativity in problem solving and a team spirit
• Knowledge of standard molecular and cell biology methods 
• Good communication/written skills 
• Passion for science, and flexibility to work some evenings and weekends
• Ability to work towards defined goals in an efficient, safe and scientifically sound manner.

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