Department of Veterinary and Animal Sciences
Faculty of Health and Medical Sciences
University of Copenhagen
A two-year Postdoc position is available in the bioinformatics group (http://ivh.ku.dk/bioinformatics), Center for non-coding RNA in Technology and Health (RTH), (http://rth.dk) at Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences at University of Copenhagen. The Postdoc position inRNA Bioinformatics and Systems Biology is available from 1 March 2018 or as soon as possible thereafter.
Information about the department can be found at http://ivh.ku.dk/english/.
You will be a team player working with great excitement and a key person in the project essential for obtaining successful results. The Postdoc position is part of the NextProd project, which aims to discover non-coding and structured RNA (ncRNA) that can affect the yield of cell factories. The Postdoc will be interacting closely with the involved people in the Vinter lab and Novozymes A/S; see http://nextprod.dk for details. The NextProd project is supported by Innovation Fund Denmark.
Cell factories are based on organisms, which have been carefully optimised to produce protein-based products such as enzymes and pharmaceutical proteins with the highest possible yield. However, current technology is saturated with respect to yield improvement although the theoretical maximum has not yet been reached. Within the NextProd project, the goal is to improve the yield by manipulating ncRNAs. See more at http://nextprod.dk.
Transcriptomic data sets from relevant strains of the model cell-factory Bacillus subtilis will be used as outset for identification of ncRNAs and their pathways through integrative analysis. This will also include in silico analysis of expression data, RNA structure and RNA-RNA interactions. An integrated workflow will be established including both known tools and tools developed on demand when relevant. The workflow will be employed directly within the context of the data generated in the project and is expected to give rise to further experimental analysis.
Required qualifications and selection criteria
The applicant should hold the professional as well as personal skills and qualifications as stated below:
• A completed PhD degree in bioinformatics, systems biology, computer science or in a similar area
• General background knowledge of biological areas of genome structure and transcriptomes
• Solid experience with transcriptome analysis
• Experience with gene network and pathway analysis
• Algorithmic insight broad and for RNA 2D structure and RNA-RNA interactions
• Strong experience with script languages such as Perl or Python (or similar)
• Strong experience with the Linux/Unix environment, command lines and shell scripting
• Familiarity or experience in at least one of the following programming languages: C, C++ or Java
• Good interpersonal skills
• Excellent in English both in writing and speech
Candidates fulfilling one or more of the following qualifications will be prioritised:
• Experience with transcriptomic data in bacteria
• Strong experience in at least one of the following programming languages: C, C++ or Java
It is recommended that applicant address the qualification requirements one by one in the cover letter.
Terms of employment
Salary and other terms and conditions of appointment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant professional organisations. The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.
The gross basic salary range for Postdoctoral Fellows is DKK 33,224 to DKK 34,980 per month (level 6 to 8). To the basic salary, a supplement could be negotiated, dependent on the candidate’s experience and qualifications. An additional 17.1 % monthly contribution to pension will be paid by the employer. Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark for the last 10 years.
The position is limited to a two-year period.
Place of employment
RTH is located on the Frederiksberg Campus; however, as part of the NextProd project research visits with project partners or collaborators will be a part of the Postdoc employment. Our research environment is highly international and stimulating. We frequently organise seminars, workshops, PhD summer schools with international speakers and have retreats with our international collaborators.