Sanford Burnham Prebys Medical Discovery Institute (SBP) is an independent nonprofit research organization that blends cutting-edge fundamental research with robust drug discovery to address unmet clinical needs in the areas of cancer, neuroscience, immunity, and metabolic disorders. The Institute invests in talent, technology, and partnerships to accelerate the translation of laboratory discoveries that will have the greatest impact on patients. Recognized for its world-class NCI-designated Cancer Center and the Conrad Prebys Center for Chemical Genomics, SBP employs about 1,000 scientists and staff in San Diego (La Jolla), Calif., and Orlando (Lake Nona), Fla. For more information, visit us at SBPdiscovery.org. The Institute can also be found on Facebook at facebook.com/SBPdiscovery and on Twitter @SBPdiscovery.
Summary:
Applications are invited from ambitious, independent and motivated candidates to join the lab of Professor Peter D. Adams investigating the epigenetics of aging and cancer at Sanford-Burnham-Prebys Medical Discovery Institute, San Diego. The specific project in the broad epigenetics-cancer-aging area can be discussed, but we are particularly interested in investigating aspects of epigenetic dysregulation in Acute Myeloid Leukemia that can be exploited for development of novel therapies.
The project can employ state-of-the-art molecular and cellular biology approaches, including ChIP-seq, RNA-seq, ATAC-seq, DNA methyl-seq and other large-scale epigenomic and chromatin analyses, including at the single-cell level; high throughput chemical and RNAi/CRISPR phenotypic screens; cell imaging; state-of-the-art gene manipulations using RNAi and CRISPR technology. In addition, we routinely employ sophisticated mouse models and human tissues.
The lab strives to be highly collaborative with other labs in San Diego, the US and elsewhere, for example collaborating with computational biologists, immunologists, experts in specific mouse models of cancer and aging, and surgeons, pathologists and clinical oncologists. San Diego is an outstanding scientific environment and a fabulous place to live.
Education and/or Experience:
Candidates should have, or be working towards, a PhD or equivalent degree in a biological science. Expertise in an aspect of cell and/or molecular biology and/or animal models is essential. The lab has dedicated computational biology support for data analysis, so computational expertise is an advantage, but not essential. Successful applicants will be able to learn computational approaches for analysis of large datasets, a big advantage in a competitive job market.
Interested candidates should send an email with a summary of achievements and research interests, updated CV and contact information for 3 letters of reference to Dr. Peter Adams (padams@sbpdiscovery.org).
Current Lab website: https://chromatin.wordpress.com
Sanford Burnham Prebys Medical Discovery Institute is an Equal Opportunity employer – M/F/Veteran/Disability – committed to the hiring, advancement and fair treatment of all individuals. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law. For additional information about your rights as an applicant, click HERE.
Sanford Burnham Prebys Medical Discovery Institute will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or © consistent with the contractor’s legal duty to furnish information.
To apply for the position, please access the Careers page of our public website at:
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